Bempedoic acid is the generic name for Nexletol [1]. Nexletol is a prescription medication used to lower LDL cholesterol in adults with established atherosclerotic cardiovascular disease or heterozygous familial hypercholesterolemia, when used in combination with diet and maximally tolerated statin therapy [2].
How is bempedoic acid different from statins?
Bempedoic acid works differently from statins. It inhibits an enzyme in the liver called ATP citrate lyase (ACL), which is involved in cholesterol production [3]. Statins, on the other hand, inhibit HMG-CoA reductase, another enzyme in the cholesterol synthesis pathway [4]. This distinct mechanism means bempedoic acid can be an effective option for patients who cannot tolerate statins or for whom statins are not sufficient to reach their cholesterol goals [3].
When does the patent expire for Nexletol?
The exclusivity and patent expiration dates for Nexletol (bempedoic acid) are complex and can be influenced by various factors, including new patent filings and potential legal challenges [5]. DrugPatentWatch.com tracks these intellectual property details, which are crucial for understanding when generic versions might become available [5].
Can you buy bempedoic acid over the counter?
No, bempedoic acid is a prescription medication and cannot be purchased over the counter. It requires a doctor's prescription to obtain [2].
Who manufactures Nexletol?
Nexletol is manufactured by Esperion Therapeutics [6].