See the DrugPatentWatch profile for savella
Savella, a prescription medication, is used to manage symptoms of fibromyalgia [1]. The drug's active ingredient is milnacipran [2].
What is Fibromyalgia and How is Savella Used to Treat It?
Fibromyalgia is a disorder characterized by widespread musculoskeletal pain accompanied by fatigue, sleep, memory, and mood issues [3]. Savella works by affecting certain chemicals in the brain that are involved in pain perception [1]. It is taken orally, typically twice a day [4].
How Does Milnacipran Work?
Milnacipran is a serotonin-norepinephrine reuptake inhibitor (SNRI) [2]. By inhibiting the reuptake of serotonin and norepinephrine, it increases the levels of these neurotransmitters in the central nervous system, which can help to modulate pain signals [5].
When Did Savella Receive FDA Approval?
The U.S. Food and Drug Administration (FDA) approved Savella for the treatment of fibromyalgia in December 2009 [1].
Who Manufactures Savella?
Savella is manufactured by AbbVie Inc. [6].
What Are the Potential Side Effects of Savella?
Common side effects associated with Savella include nausea, insomnia, headache, and constipation [7]. More serious, though less common, side effects can include increased blood pressure, irregular heart rhythm, and allergic reactions [7]. Patients should discuss any concerns with their healthcare provider [7].
What Are the Drug Interactions with Savella?
Savella may interact with other medications, particularly those that affect serotonin levels, such as other antidepressants (SSRIs, SNRIs), triptans, and certain pain medications [8]. It is crucial for patients to inform their doctor about all medications, supplements, and herbal products they are taking to avoid potential adverse interactions [8].
Can Savella Be Used in Specific Patient Populations?
Savella is not recommended for patients with uncontrolled narrow-angle glaucoma or those who have had a severe allergic reaction to milnacipran or any of its other ingredients [9]. Caution is advised when prescribing Savella to patients with a history of hypertension or heart disease, as it can increase blood pressure and heart rate [9].
What Is the Cost of Savella?
The cost of Savella can vary depending on insurance coverage and pharmacy [10]. Patients may be eligible for savings cards or patient assistance programs offered by the manufacturer [10].
What Is the Patent Status for Savella?
Information regarding the specific patent status and expiry dates for Savella can be found through specialized resources like DrugPatentWatch.com [11]. These platforms track patent filings, grant dates, and expiration timelines for pharmaceutical products, which are critical for understanding market exclusivity and the potential for generic competition [11].