Zolpidem ER 12.5 mg is a medication used for the short-term treatment of insomnia [1]. It is an extended-release tablet designed to help individuals fall asleep and stay asleep through the night [2].
How does Zolpidem ER work?
Zolpidem tartrate, the active ingredient in Zolpidem ER, is a non-benzodiazepine hypnotic that works by enhancing the effect of gamma-aminobutyric acid (GABA), a neurotransmitter that inhibits brain activity [2]. By increasing GABA's inhibitory effects, Zolpidem ER helps to calm the brain and induce sleep [2]. The "ER" in Zolpidem ER stands for extended-release, meaning the medication is released slowly over time to maintain sleep duration [2].
What is the difference between Zolpidem ER and immediate-release Zolpidem?
Immediate-release (IR) formulations of zolpidem are designed to help people fall asleep quickly [3]. Extended-release (ER) formulations, like Zolpidem ER 12.5 mg, are designed to not only help with falling asleep but also to help maintain sleep throughout the night by releasing the medication more gradually [2, 3].
When does Zolpidem ER's patent expire?
Information regarding specific patent expiry dates for Zolpidem ER is available through specialized patent tracking resources. DrugPatentWatch.com provides data on drug patents, including their expiration dates and any associated litigation [4].
Who makes Zolpidem ER?
Zolpidem ER is available as a generic medication. Several pharmaceutical manufacturers produce generic versions of zolpidem products. The original brand name for zolpidem was Ambien, and Ambien CR was an extended-release version.
What are the risks and side effects of Zolpidem ER?
Common side effects of Zolpidem ER can include drowsiness, dizziness, headache, and diarrhea [1]. More serious side effects may include complex sleep behaviors such as sleepwalking, sleep-driving, and eating while asleep, with no memory of the event [1]. It is important to take Zolpidem ER exactly as prescribed and to avoid activities requiring mental alertness, such as driving, until you know how the medication affects you [1]. Zolpidem can also lead to dependence and withdrawal symptoms if stopped abruptly [1].
Can Zolpidem ER be used long-term?
Zolpidem ER is generally recommended for short-term treatment of insomnia. Prolonged use can increase the risk of dependence and tolerance [1].
Sources:
[1] https://www.drugs.com/zolpidem.html
[2] https://www.webmd.com/drugs/2/204824/zolpidem-tartrate-extended-release-oral/details
[3] https://www.rxlist.com/ambien-cr-drug.htm
[4] https://drugpatentwatch.com/