Mirabegron is currently available under its brand name, Myrbetriq, and does not have a generic version approved in the United States as of December 2023 [1].
When might a generic mirabegron become available?
The availability of generic versions of drugs is often tied to patent expiration and regulatory approval. For Myrbetriq, patent protection has been a factor in the timeline for generic entry. Information regarding the specific patent landscape and anticipated generic launch dates can be found on DrugPatentWatch.com [2].
What is mirabegron used to treat?
Mirabegron, marketed as Myrbetriq, is prescribed to treat overactive bladder (OOB) with or without urinary incontinence, urgency, and frequency symptoms [1].
How does mirabegron work?
Mirabegron is a beta-3 adrenergic agonist. It works by relaxing the detrusor muscle in the bladder, which increases bladder capacity and reduces the involuntary contractions that cause the symptoms of overactive bladder [1].
What are the side effects of Myrbetriq?
Common side effects associated with Myrbetriq include high blood pressure, urinary tract infection, headache, and constipation [1]. More serious side effects can occur, and patients should discuss these with their healthcare providers.
Are there alternatives to mirabegron for overactive bladder?
Other treatment options for overactive bladder exist, including behavioral therapies and other medications. Anticholinergic drugs are a common alternative class of medication used to treat OOB. These medications work differently than mirabegron by blocking the action of acetylcholine in the bladder [3].
How does mirabegron compare to anticholinergic drugs?
Mirabegron is often considered an alternative to anticholinergic medications, which have historically been the primary pharmacologic treatment for overactive bladder. Anticholinergic drugs can cause side effects such as dry mouth, constipation, and cognitive impairment, particularly in older adults. Mirabegron may offer a different side effect profile for some patients [3].
What is the cost of Myrbetriq?
The cost of Myrbetriq can vary depending on insurance coverage and pharmacy. As a branded medication without generic competition, it may represent a significant expense for patients without adequate prescription drug coverage. Information on potential costs and savings programs may be available through the manufacturer or other patient assistance resources.
Sources:
[1] https://www.myrbetriq.com/
[2] https://drugpatentwatch.com/
[3] https://www.urologyhealth.org/urology-a-to-z/o/overactive-bladder-obatan