Standard Yervoy Dosing Schedule
Yervoy (ipilimumab), used for advanced melanoma and other cancers, is typically given every 3 weeks for four doses in the induction phase. This totals 10 mg/kg intravenously over 90 minutes per dose.[1]
Maintenance and Combination Regimens
After induction, some patients receive maintenance doses every 3 months up to year 3, or as needed based on response. In combinations like Yervoy + Opdivo (nivolumab), it's often every 3 weeks for four doses, followed by Opdivo alone every 2 or 4 weeks.[1][2]
Duration and Adjustments
Treatment lasts 3 years maximum in many protocols, but doctors adjust for toxicity or progression. Doses may delay or reduce (e.g., to 3 mg/kg) if severe side effects occur.[1]
Factors Affecting Frequency
Dosing depends on cancer type, weight, kidney/liver function, and response. Pediatric use follows body surface area calculations. Always follow oncologist guidance—self-adjusting risks severe immune reactions.[2]
Common Patient Questions on Scheduling
Patients often ask about missed doses (resume ASAP if within schedule) or infusion timing (outpatient, 90 minutes).[2] No oral form exists; it's IV only.
[1]: Yervoy Prescribing Information (Bristol Myers Squibb)
[2]: Drugs.com - Yervoy Dosage Guide