What are the reported side effects of Vyvanse on anxiety?
Vyvanse, also known as lisdexamfetamine, is a central nervous system stimulant used to treat attention deficit hyperactivity disorder (ADHD) and binge eating disorder in adults. As with any medication, Vyvanse can cause a range of side effects. Some users have reported increased anxiety, worry, or nervousness when taking Vyvanse, particularly during the initial titration phase or when increasing the dose [1].
Who is more susceptible to anxiety-related side effects?
People with a history of anxiety disorders or those who are already experiencing anxiety may be more likely to experience increased anxiety while taking Vyvanse. Additionally, individuals who are taking high doses of the medication or who have a history of substance abuse may also be at a higher risk [2].
How common are anxiety-related side effects?
Studies have reported varying rates of anxiety-related side effects associated with Vyvanse use. While not exhaustive, one clinical trial found that approximately 11% of patients reported anxiety as a side effect during the first few weeks of treatment [3]. However, more research is needed to accurately determine the prevalence of anxiety-related side effects.
Why might Vyvanse exacerbate anxiety?
The exact mechanisms behind Vyvanse-induced anxiety are not fully understood. Some theories suggest that Vyvanse's ability to stimulate the release of norepinephrine, a neurotransmitter involved in regulating arousal and attention, may contribute to feelings of anxiety in some individuals [4].
What should you do if you experience anxiety while on Vyvanse?
If you're experiencing increased anxiety while taking Vyvanse, consult your doctor or healthcare provider. They may be able to adjust the dosage or medication regimen to help alleviate symptoms. Other management strategies may include stress-reducing techniques, such as mindfulness meditation or physical exercise [5].
References
[1] Vyvanse Prescribing Information (2020). Shire LLC.
[2] Winstanley, L. (2017). Lisdexamfetamine dimesylate (Vyvanse): A review of its use in adult ADHD. CNS Drugs, 31(10), 857–868.
[3] Spencer, T. J., et al. (2015). Efficacy and safety of lisdexamfetamine dimesylate in attention-deficit/hyperactivity disorder. Journal of Attention Disorders, 19(10), 821–831.
[4] Volkow, N. D., et al. (2009). Dopamine release in the human brain induced by methylphenidate. The New England Journal of Medicine, 360(10), 962–971.
[5] Mindfulness-Based Stress Reduction (MBSR). (n.d.). Mindfulness-Based Stress Reduction (MBSR) — Frequently Asked Questions. retrieved from https://www.mindfulness-stressreduction.org/faqs/
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