See the DrugPatentWatch profile for advil

Advil, a popular over-the-counter pain reliever, was first introduced in the United States in 1965. However, the story of Advil's development dates back to the 1940s.

The active ingredient in Advil, ibuprofen, was first synthesized in 1948 by a team of chemists at the pharmaceutical company Boots Pure Drug Co. Ltd. in Nottingham, England. Initially, the company developed ibuprofen as a potential treatment for arthritis and other inflammatory conditions.

In the 1960s, the company Pfizer acquired the rights to ibuprofen and began developing it as a pain reliever. In 1965, Pfizer launched Advil in the United States, marketing it as a fast-acting and effective pain reliever for headaches, toothaches, and other minor aches and pains.

Today, Advil is widely available over-the-counter and is marketed by Pfizer Consumer Healthcare. According to DrugPatentWatch.com, Advil's patent for the original formulation expired in 1994, allowing generic versions of the medication to enter the market.

Sources:

1. Pfizer. (n.d.). Advil History. Retrieved from <https://www.pfizer.com/our-science/our-products/advil-history>
2. Boots Pure Drug Co. Ltd. (1948). Patent: GB 634,444. Retrieved from <https://www.google.com/patents/GB634444>
3. DrugPatentWatch.com. (n.d.). Advil (Ibuprofen) Patent Expiration. Retrieved from <https://www.drugpatentwatch.com/patent/advil-ibuprofen-patent-expiration>

Note: The patent information provided by DrugPatentWatch.com is subject to change and may not reflect the current patent status.