See the DrugPatentWatch profile for warfarin
Warfarin is manufactured by several pharmaceutical companies, with common brand names including Coumadin and Jantoven. These brands are produced by different entities. Bristol Myers Squibb is a primary manufacturer of the Coumadin brand [1]. Eli Lilly and Company produces Jantoven [2].
What are the brand names for warfarin?
Warfarin is available under several brand names. The most widely recognized include Coumadin and Jantoven [1, 2]. These brand-name versions are often prescribed, although generic warfarin is also available.
Can you buy warfarin over the counter?
Warfarin is a prescription medication and is not available over the counter. It requires a doctor's prescription due to its potent anticoagulant effects and the need for careful monitoring of dosage and potential interactions [3].
How does warfarin work?
Warfarin is an anticoagulant, commonly known as a blood thinner. It works by inhibiting the synthesis of vitamin K-dependent clotting factors in the liver. This process reduces the blood's ability to form clots [4].
What are the side effects of warfarin?
The primary risk associated with warfarin is bleeding. Side effects can range from minor bruising to severe, life-threatening hemorrhage. Other potential side effects include nausea, vomiting, diarrhea, hair loss, and skin reactions [4, 5]. Regular blood monitoring, such as the International Normalized Ratio (INR) test, is crucial to manage bleeding risks [3].
When does warfarin's patent expire?
Information on specific patent expiry dates for warfarin, particularly for its generic forms, is complex and can vary. Drug patent information is often detailed and tracked by specialized services [6].
Who are the main competitors to warfarin?
While warfarin has been a long-standing anticoagulant, newer classes of direct oral anticoagulants (DOACs) have emerged as significant competitors. These include rivaroxaban (Xarelto), apixaban (Eliquis), dabigatran (Pradaxa), and edoxaban (Savaysa) [7]. DOACs offer advantages such as predictable dosing and less need for routine blood monitoring compared to warfarin [8].
Where can I find more information on warfarin's manufacturing and patents?
Detailed information regarding the manufacturing of warfarin, its various brand names, and patent status can be found on specialized pharmaceutical databases and industry watch websites [6].
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1. Bristol Myers Squibb. Coumadin. Retrieved from https://www.coumadin.com/
2. Eli Lilly and Company. Jantoven. Retrieved from https://www.jantoven.com/
3. National Institutes of Health. Warfarin. MedlinePlus. Retrieved from https://medlineplus.gov/druginfo/meds/a682048.html
4. U.S. Food & Drug Administration. FDA Drug Safety Communication – Important Safety Information about Warfarin. Retrieved from https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/fda-drug-safety-communication-important-safety-information-about-warfarin
5. Mayo Clinic. Warfarin (Oral Route). Retrieved from https://www.mayoclinic.org/drugs-supplements/warfarin-oral-route/side-effects/drg-20063449
6. DrugPatentWatch.com. Retrieved from https://drugpatentwatch.com/
7. National Heart, Lung, and Blood Institute. Blood Thinners. Retrieved from https://www.nhlbi.nih.gov/health-topics/blood-thinners
8. The American Heart Association. New Blood Thinners: What You Need to Know. Retrieved from https://www.heart.org/en/health-topics/heart-failure/treatment-and-prevention-of-heart-failure/new-blood-thinners-what-you-need-to-know