Does cosentyx affect covid 19 vaccine's immune response?

Short answer: In general, cosentyx (secukinumab) does not strongly suppress the immune response to COVID-19 vaccines, and vaccination is considered safe and recommended for people taking this medicine. Most available data suggest people on secukinumab can mount a good antibody response to mRNA COVID-19 vaccines, though studies are smaller and data are still evolving.

Key points:
- Safety: COVID-19 vaccines are non-live and safe to receive while on secukinumab. There’s no need to stop cosentyx just to get vaccinated unless your clinician advises it for another reason.
- Effect on vaccine response: IL-17 inhibitors like secukinumab may have a smaller impact on vaccine responses compared with some other immunosuppressants (e.g., B-cell–depleting therapies). Most studies in psoriasis/psoriatic arthritis populations show preserved or near-normal antibody responses after COVID-19 vaccination. However, individual responses can vary.
- Practical tips:
- If you’re due for a vaccine, you can usually receive it without pausing cosentyx.
- If you’re also on other immunosuppressants (e.g., methotrexate), your clinician might have specific guidance. Some doctors consider temporarily holding certain medicines around vaccination to improve response, but this depends on the medication and your condition.
- Keep up with boosters as recommended by health authorities; vaccine timing and number of doses can depend on your age, health status, and the vaccines available.

If you’d like, I can summarize the latest studies on secukinumab and COVID-19 vaccine responses (and note any differences by vaccine type). Also, if you’re planning a vaccine, tell me which vaccine you’re getting (Pfizer/Moderna/Janssen, etc.) and your exact condition, and I can tailor the info. Always follow your rheumatologist’s guidance for your specific situation.