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See the DrugPatentWatch profile for calcium
Dihydropyridine (DHP) calcium channel blockers lower blood pressure by relaxing vascular smooth muscle. Common DHPs include: - Amlodipine - Nifedipine (including extended-release forms) - Felodipine (often extended-release) - Nicardipine - Isradipine - Lacidipine - Lercanidipine - Nimodipine - Nisoldipine - Verapamil and diltiazem are not dihydropyridines (they are non-dihydropyridine agents).
Nifedipine is available in different formulations. Immediate-release nifedipine can act faster, while extended-release formulations are designed to release the drug more slowly and are often used to reduce fluctuation in drug levels.
Common DHP side effects include ankle/leg swelling (peripheral edema), flushing, headache, dizziness, and sometimes reflux-like symptoms. Peripheral edema is particularly common with some DHPs (notably amlodipine). If you tell me which specific drug name(s) you’re considering, I can flag the most relevant side-effect and interaction considerations.
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