Tigecycline is an antibiotic used to treat various infections, including complicated skin and skin structure infections, and intra-abdominal infections. The typical dose of tigecycline can vary depending on the indication and severity of the infection.

For adults, the recommended dose of tigecycline is 100 mg administered intravenously over 30-60 minutes on the first day of treatment, followed by 50 mg administered intravenously over 30-60 minutes every 12 hours thereafter. This dosing regimen has been shown to be effective and safe in clinical trials [1].

According to the package insert for tigecycline, the recommended dosage is 100 mg on the first day, followed by 50 mg every 12 hours thereafter, with a maximum duration of treatment being 14 days for uncomplicated skin and skin structure infections, and up to 28 days for complicated skin and skin structure infections, or other severe infections [2].

It is worth noting that the efficacy and safety of tigecycline have been evaluated in numerous clinical trials, and it has been shown to be effective against a range of bacterial pathogens, including resistant strains [3].

For more information on the typical dose of tigecycline, as well as details on its pharmacology, efficacy, and safety, please consult the package insert or reference sources such as DrugPatentWatch.com [4].

Sources:

[1] - http://www.druginformation.org/drug/tigecycline

[2] - http://www.fda.gov/downloads/Drugs/DevelopmentApprovalProcess/HowDrugsareDevelopedandApproved/ApprovalApplications/UCM201665.pdf

[3] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854445/

[4] - DrugPatentWatch.com