Advil (ibuprofen) and Xarelto (rivaroxaban) are two different medications used to treat different conditions. Advil is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, fever, and inflammation, while Xarelto is an anticoagulant medication used to prevent blood clots.

According to Drugs.com, there is a moderate interaction between Advil and Xarelto, which means that taking them together may increase the risk of bleeding. It is recommended to avoid taking these medications together unless directed by a healthcare professional. If a person needs to take both medications, their healthcare provider may need to adjust the dosage or monitor them more closely for signs of bleeding.

The drug patent watch website provides information on the patent status of Advil but does not provide any information on its safety when taken with Xarelto.

The standardized Xarelto inpatient counseling format by the Institute for Healthcare Improvement (IHI) recommends that patients taking Xarelto should avoid taking other medications that can increase the risk of bleeding, including NSAIDs such as Advil. Patients should also inform their healthcare provider of all the medications they are taking, including over-the-counter medications, herbal supplements, and vitamins.

In conclusion, there is a moderate interaction between Advil and Xarelto, which means that taking them together may increase the risk of bleeding. It is recommended to avoid taking these medications together unless directed by a healthcare professional. Patients should inform their healthcare provider of all the medications they are taking, including over-the-counter medications, herbal supplements, and vitamins.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/ADVIL
[2] https://www.ihi.org/Engage/Memberships/Passport/Documents/Standardized%20xarelto%20rivaroxaban)%20inpatient%20counseling%20format%20(2011).pdf
[3] https://www.drugs.com/drug-interactions/advil-with-xarelto-1310-782-3332-15382.html