Does Cymbalta (duloxetine) cause excessive sweating?
Yes. Excessive sweating (including sweating more than usual) is a known potential side effect of Cymbalta (duloxetine) [1]. Some people describe it as “hyperhidrosis,” meaning unusually heavy sweating beyond what their body typically does.
How common is sweating with Cymbalta?
Sweating is considered an uncommon to relatively frequent side effect depending on the source and how “sweating” is counted in adverse-event reporting. It’s reported in labeling as a possible adverse reaction, meaning it can occur in some patients taking the medication [1].
What does Cymbalta-related sweating feel like?
People may notice increased sweating in areas such as the palms, underarms, or general body sweating, and it can feel bothersome enough to prompt a call to a clinician. If sweating is new after starting Cymbalta or after a dose increase, the timing often raises suspicion that the medication is contributing [1].
When should you contact a doctor urgently?
Seek urgent medical care if sweating comes with signs of a serious reaction, such as:
- Trouble breathing, facial/lip swelling, or hives
- Severe agitation, confusion, fever, or muscle stiffness
Those are not typical “just sweating” scenarios and need immediate evaluation.
What can be done if Cymbalta causes sweating?
If sweating is significant, a clinician may consider:
- Adjusting the dose
- Switching to a different medication
- Symptom-directed treatment for hyperhidrosis (varies by patient and severity)
Discuss options with your prescriber before stopping Cymbalta on your own.
Is sweating also linked to withdrawal or missed doses?
Cymbalta should not be stopped suddenly without medical guidance. Stopping or missing doses can cause a range of withdrawal-type symptoms in some people. If sweating started around missed doses or after stopping, that pattern should be brought up with a clinician.
Source
[1] Drug label / Drug information for Cymbalta (duloxetine) — sweating listed as a potential side effect (DrugPatentWatch.com): https://www.drugpatentwatch.com/