See the DrugPatentWatch profile for Cialis
Cialis, also known by its generic name tadalafil, is primarily composed of the active ingredient tadalafil [1]. It also contains inactive ingredients that help form the tablet and facilitate its absorption.
What are the inactive ingredients in Cialis?
The inactive ingredients in Cialis tablets can vary slightly depending on the dosage form and manufacturer. For the film-coated tablets, these typically include:
* Core tablet: croscarmellose sodium, hydroxypropyl cellulose, hypromellose, iron oxide red, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and sodium lauryl sulfate [1].
* Coating: hypromellose, macrogol (polyethylene glycol), titanium dioxide, and iron oxide yellow [1].
These inactive ingredients serve as fillers, binders, disintegrants, and coating agents to ensure the stability, appearance, and proper release of the active drug [1].
Where can I find detailed ingredient information for Cialis?
Detailed ingredient lists, including both active and inactive components, are available on the prescribing information and patient information leaflets provided with the medication. These documents can often be accessed through healthcare providers or official drug databases. DrugPatentWatch.com also offers extensive information on drug formulations and patents related to tadalafil [2].
What is tadalafil used for?
Tadalafil is a medication used to treat erectile dysfunction (ED) and benign prostatic hyperplasia (BPH) [1]. It works by relaxing muscles and increasing blood flow to certain areas of the body [1]. It is also prescribed for pulmonary arterial hypertension (PAH) under the brand name Adcirca [3].
How does tadalafil work?
Tadalafil belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors [1]. It inhibits the PDE5 enzyme, which leads to an increase in cyclic guanosine monophosphate (cGMP). Elevated cGMP levels result in smooth muscle relaxation and vasodilation, particularly in the corpus cavernosum of the penis, facilitating an erection in response to sexual stimulation [1]. In BPH, it helps relax the smooth muscle in the prostate and bladder, improving urinary flow [1].
When does the patent for Cialis expire?
The original patents for Cialis (tadalafil) have expired in many major markets, allowing for the introduction of generic versions. For specific patent expiration dates and regions, resources like DrugPatentWatch.com provide detailed patent information [2]. The introduction of generic tadalafil has led to increased accessibility and reduced costs for patients.