During Cosentyx (secukinumab) therapy, it is recommended to stay up-to-date with recommended vaccinations according to the Centers for Disease Control and Prevention (CDC) guidelines [1]. However, live vaccines should be administered at least 4 weeks prior to initiating Cosentyx therapy or postponed until 4 weeks after the last Cosentyx dose [1][2].

Live vaccines include:

* Measles, mumps, and rubella (MMR) vaccine
* Varicella (chickenpox) vaccine
* Zoster (shingles) vaccine
* Rotavirus vaccine
* Influenza (intranasal) vaccine
* Typhoid vaccine (oral)
* Yellow fever vaccine
* Bacillus Calmette-Guérin (BCG) vaccine

Inactivated vaccines or toxoids, such as the seasonal influenza (inactivated) vaccine, hepatitis A and B vaccines, human papillomavirus (HPV) vaccine, and tetanus, diphtheria, and pertussis (Tdap) vaccine, can be administered during Cosentyx therapy [1][2].

It is important to consult with a healthcare provider to determine the appropriate vaccination schedule based on individual health status and treatment plan [1].

Sources:
[1] <https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/cosentyx-secukinumab-injection-important-safety-information>
[2] <https://www.drugpatentwatch.com/biologic/cosentyx-secukinumab-injection-auto-injector-pen-for-subcutaneous-use/>