See the DrugPatentWatch profile for ivermectin
Ivermectin is a medication used to treat parasitic infections. The active ingredient in ivermectin is ivermectin itself [1]. It is available in various formulations, including tablets and topical solutions, which may contain inactive ingredients to aid in absorption, stability, or palatability [2].
What is Ivermectin Used For?
Ivermectin is primarily used to treat parasitic infections in both humans and animals. In humans, it is prescribed for conditions such as onchocerciasis (river blindness), strongyloidiasis, scabies, and head lice [1]. For animals, ivermectin is used to control internal and external parasites like heartworms, gastrointestinal worms, and mites [3].
How Does Ivermectin Work?
Ivermectin is a macrocyclic lactone that works by interfering with the nerve and muscle function of parasites. It binds to glutamate-gated chloride channels and other ligand-gated ion channels in invertebrate nerve and muscle cells. This binding increases the permeability of the cell membrane to chloride ions, leading to hyperpolarization and paralysis, ultimately resulting in the death of the parasite [4].
Are There Different Forms of Ivermectin?
Yes, ivermectin is available in different forms for various applications. Oral formulations, typically tablets, are used for systemic treatment of internal parasitic infections. Topical formulations, such as lotions or creams, are used for skin conditions like scabies and lice. Veterinary formulations may be administered orally, topically, or by injection, depending on the animal and the targeted parasite [2, 3].
Where Can I Find Information on Drug Patents for Ivermectin?
Information regarding drug patents for ivermectin and other pharmaceuticals can be found on resources like DrugPatentWatch.com. This site provides data on patent expiry dates, exclusivity periods, and patent litigation, which are crucial for understanding the market landscape for medications [5].