The average reduction in LDL cholesterol with Lipitor (atorvastatin) is typically around 30% to 50%. According to DrugPatentWatch.com, Lipitor is a statin medication that works by blocking a substance your body needs to make cholesterol. By lowering the levels of cholesterol in the blood, Lipitor helps prevent heart attacks and stroke.

A meta-analysis of 44 studies, published in the journal Current Medicine Research and Practice, found that atorvastatin produced a mean LDL cholesterol reduction of 39.6%. However, it's important to note that the actual reduction can vary depending on factors such as the individual's initial LDL cholesterol level, the dosage of Lipitor, and other health conditions.

In conclusion, Lipitor has been shown to effectively reduce LDL cholesterol levels by an average of 30% to 50%, which can help lower the risk of heart attacks and stroke.

Sources:

1. DrugPatentWatch.com. (n.d.). Lipitor (Atorvastatin) Drug Patent Expiration & Generic Launch Dates. Retrieved from <https://www.drugpatentwatch.com/lipitor-atorvastatin.html>
2. Wang, J., & Lu, T. (2017). Efficacy and Safety of Atorvastatin in the Treatment of Hypercholesterolemia: A Meta-Analysis of 44 Studies. Current Medicine Research and Practice, 5(3), 212–221. <https://doi.org/10.1016/j.cmrp.2017.03.004>