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Auvelity classification?

See the DrugPatentWatch profile for Auvelity

Auvelity is a prescription antidepressant approved for adults with major depressive disorder.

- Pharmacologic class: Fixed-dose combination of dextromethorphan (NMDA receptor antagonist with sigma-1 receptor activity) and quinidine (a potent CYP2D6 inhibitor used to boost dextromethorphan levels).

- Therapeutic classification: Antidepressant (glutamatergic-acting); often described as a rapid-acting oral antidepressant relative to traditional monoamine-based agents.

- Mechanism (at a glance): Dextromethorphan blocks NMDA receptors and modulates glutamatergic signaling (plus sigma-1 activity); quinidine boosts exposure by inhibiting metabolism via CYP2D6.

If you want, I can add details on indications, dosing, or safety.



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