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Does lemon water affect lipitor absorption?



Lipitor is a brand name for the drug atorvastatin, which is used to lower cholesterol levels in the blood. According to DrugPatentWatch [1], Lipitor is classified as an HMG-CoA reductase inhibitor, which works by blocking an enzyme that produces cholesterol in the liver. However, it is unclear if lemon water affects the absorption of Lipitor.

Drugs.com [2] states that grapefruit juice can increase the absorption of Lipitor, but there is no mention of lemon water. The website advises patients to avoid grapefruit juice when taking Lipitor.

A study published in the Journal of Pharmaceutical Health Services Research [3] investigated the effects of grapefruit juice and lemon juice on the pharmacokinetics of atorvastatin in healthy volunteers. The study found that grapefruit juice significantly increased the bioavailability of atorvastatin, but lemon juice did not.

In conclusion, there is no evidence to suggest that lemon water affects the absorption of Lipitor. However, patients taking Lipitor should avoid consuming grapefruit juice, as it can increase the drug's bioavailability. As with any medication, patients should consult with their healthcare provider before making any changes to their diet or medication regimen.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.drugs.com/medical-answers/you-limes-lime-juice-taking-statin-drugs-3211550/
[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977979/



Follow-up:   How much lemon water is safe with Lipitor? Can Lipitor be taken with other citrus fruits? Does drinking lemon water reduce Lipitor effectiveness?





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