Standard Ozempic Dosing Schedule
Ozempic (semaglutide) is injected subcutaneously once per week. Patients typically receive one injection weekly, regardless of dose strength.[1]
How the Weekly Dose Escalates
Dosing starts at 0.25 mg once weekly for 4 weeks to minimize side effects, then increases to 0.5 mg once weekly for at least 4 weeks. It can go up to 1 mg or 2 mg once weekly based on response and tolerance. Each escalation keeps the once-weekly frequency.[1][2]
What If a Dose Is Missed?
Inject the missed dose as soon as possible within 5 days, then resume the weekly schedule. If more than 5 days have passed, skip it and take the next dose on the regular day. Never double up.[1]
Why Once Weekly Instead of Daily?
Ozempic's long half-life (about 1 week) allows steady blood levels with one injection, improving adherence over daily options like some older diabetes drugs.[2]
Ozempic vs. Other Semaglutide Products
Wegovy (higher doses for weight loss) and Rybelsus (daily oral) use semaglutide but follow different schedules—Wegovy is also weekly, Rybelsus daily. Prescriptions specify the product.[1][3]
[1]: Ozempic Prescribing Information (Novo Nordisk)
[2]: FDA Label for Ozempic
[3]: Drugs.com - Ozempic Dosage