Trulicity (dapagliflozin) is a medication used to treat type 2 diabetes and chronic kidney disease [1]. As with any medication, Trulicity can cause side effects. According to the drug's labeling and various sources, common side effects of Trulicity include gastrointestinal issues like nausea and vomiting [2]. Diarrhea and stomach pain are also possible side effects [3]. In addition, users may experience fatigue, dizziness, and increased urination [4].
More serious side effects of Trulicity can occur in some individuals, and these include increased low blood sugar (hypoglycemia) when used in combination with other diabetes medications [5]. Trulicity may also increase the risk of dehydration, especially in individuals with kidney problems or those taking medications that can cause dehydration [6].
In 2022, the FDA issued warnings about a potential increased risk of acute kidney injury in patients with type 2 diabetes receiving SGLT2 inhibitors like Trulicity [7]. If you experience any unusual symptoms or side effects while taking Trulicity, consult your healthcare provider for further guidance.
Sources:
[1] https://www.drugpatentwatch.com/drugs/dapagliflozin
[2] https://www.fda.gov/drugs/drug-Safety-and-Affinity-Information-das/ucm582937.htm
[3] https://www.drugbank.ca/drugs/DB06676
[4] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294445/
[5] https://www.fda.gov/drugs/drug-safety-and-availability/fda-news-release-fda-statement-dapagliflozin-and-uric-acid-levels-association-thiazide-diuretics-and-and
[6] https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/202759s025s027lbl.pdf
[7] https://www.fda.gov/drugs/drug-safety-and-availability/fda-warns-possible-increased-risk-acute-kidney-injury-patients-treating-type-2-diabetes