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See the DrugPatentWatch profile for Ephedrine
Ephedrine injection is a sympathomimetic drug used mainly as a vasopressor to support blood pressure. Its primary and common uses include: - Treating intraoperative hypotension, especially due to spinal/epidural anesthesia or anesthesia-related drops in blood pressure. - Supporting blood pressure in acute hypotensive states (e.g., shock) when fluids alone are insufficient, typically in hospital/ICU settings. - Treating bradycardia with accompanying hypotension during procedures (the drug can increase both BP and heart rate). Less commonly, historically it has been used for bronchodilation, but this is not a first-line use today. Notes on administration and safety: - Dosing is determined by clinicians and is usually given as small IV boluses (for example, 5–10 mg per dose) and titrated to achieve the desired blood pressure; sometimes given as a continuous low-dose infusion. - Contraindications and cautions: not suitable in tachyarrhythmias, uncontrolled hypertension, significant coronary artery disease, pheochromocytoma, or hypersensitivity. Use with caution in patients with thyrotoxicosis, glaucoma, or severe vascular disease; MAO inhibitors can interact and enhance effects. - Common side effects include tachycardia, hypertension, arrhythmias, tremor, nervousness, and insomnia. If you want, I can give more detail about specific anesthesia settings, ICU scenarios, or general dosing ranges.
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