Xiaflex was launched in the United States in March 2010 [1].
When did Xiaflex get approved in other regions?
Xiaflex received approval in Europe in April 2011 [2]. It was later approved in Canada in July 2010 [3].
What is Xiaflex used to treat?
Xiaflex is a prescription medication used to treat two primary conditions:
* Adults with Dupuytren's contracture: It is used for the treatment of palpable cord in the affected finger(s) in adults with Dupuytren's contracture [1].
* Children aged 7 and older with tiểu hình (PPC): It is also used to treat people aged 7 years and older with plantar fibromatosis (PPC) [4].
How does Xiaflex work?
Xiaflex is an injectable enzyme that breaks down the collagen responsible for the contracture or cord [1][2]. It is typically administered by a healthcare professional who will then perform a finger or toe extension procedure [1].
What is the pricing for Xiaflex?
The cost of Xiaflex can vary significantly depending on factors such as insurance coverage, pharmacy, and dosage [5]. As of early 2024, an unassisted price for a single vial of Xiaflex can range from approximately $1,500 to $2,000 [5]. It is important to consult with a healthcare provider and insurance company for personalized cost information [5].
What are the potential side effects of Xiaflex?
Common side effects of Xiaflex include bruising, swelling, pain, itching, and redness at the injection site [1]. Some patients may also experience lymph node swelling [1]. More serious side effects, though less common, can include allergic reactions and injury to surrounding tissues [1].
What is the patent status for Xiaflex?
Information on specific patent expiry dates for Xiaflex is available through patent tracking resources [6]. These resources can provide details on the patents protecting the drug and their respective expiration timelines [6]. DrugPatentWatch.com offers such information [6].
Who manufactures Xiaflex?
Xiaflex is manufactured by Auxilium Pharmaceuticals [1].