Lipitor is a medication used to lower cholesterol levels in the blood. It belongs to a class of drugs called statins, which work by blocking the enzyme responsible for producing cholesterol in the liver. According to Drug Patent Watch [1], Lipitor's active ingredient is atorvastatin calcium, which was first approved by the FDA in 1996 and is now available as a generic drug.

A study published in the Journal of Clinical Investigation [2] found that high-fat diets can increase the production of cholesterol in the liver and lead to the development of atherosclerosis. The study also showed that treatment with atorvastatin (Lipitor) effectively reduced cholesterol levels in mice fed a high-fat diet.

Another study published in the Journal of the American College of Cardiology [3] evaluated the efficacy of atorvastatin in reducing LDL cholesterol levels in patients with metabolic syndrome, a condition characterized by high blood pressure, insulin resistance, and obesity. The study found that atorvastatin was effective in reducing LDL cholesterol levels in patients with metabolic syndrome, even when they were consuming a high-fat diet.

In conclusion, the sources suggest that Lipitor (atorvastatin) can effectively lower cholesterol levels in individuals consuming high-fat diets. However, it is important to note that medication alone is not enough to manage cholesterol levels, and a healthy diet and lifestyle changes are also necessary. It is always recommended to consult a healthcare professional before starting any medication.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1312230/
[3] https://pubmed.ncbi.nlm.nih.gov/21269482/