The price of Mavyret can vary. In the United States, the average retail price for a 14-day supply of Mavyret is approximately $26,000 [1]. However, actual costs for patients can be lower due to insurance coverage, patient assistance programs, or copay cards.
How much does Mavyret cost with insurance?
Insurance coverage for Mavyret significantly impacts out-of-pocket costs. Many insurance plans cover Mavyret, but copayments and deductibles will depend on the specific policy. Some insurers may require prior authorization or step therapy, meaning other treatments must be tried first. Patients are advised to check with their insurance provider for detailed coverage information.
Are there patient assistance programs for Mavyret?
Yes, AbbVie, the manufacturer of Mavyret, offers patient assistance programs. The AbbVie Patient Assistance Foundation may provide Mavyret at no cost to eligible uninsured and underinsured patients who meet certain income and residency requirements. Additionally, copay cards are available for commercially insured patients, which can reduce out-of-pocket expenses for eligible individuals. Information on these programs can be found on the Mavyret website or by contacting AbbVie patient services.
What is the difference between Mavyret and other hepatitis C treatments?
Mavyret is a pan-genotypic treatment for chronic hepatitis C virus (HCV) infection, meaning it is effective against all common genotypes of the virus [2]. It is a combination pill containing glecaprevir and pibrentasvir and is typically taken for eight weeks in patients without cirrhosis [3]. Other HCV treatments may have different durations, target specific genotypes, or involve different drug combinations and administration methods. The effectiveness, side effect profiles, and treatment durations can vary among different medications used to treat hepatitis C.
When does Mavyret's patent expire?
The patent landscape for pharmaceuticals is complex, involving multiple patents covering different aspects of a drug. Information on specific patent expiry dates for Mavyret can be found through specialized patent tracking services [4]. These services track the patents that protect drugs from generic competition.
Who makes Mavyret?
Mavyret is manufactured by AbbVie [2].
What are the clinical trial results for Mavyret?
Clinical trials for Mavyret have demonstrated high sustained virologic response (SVR) rates, which is the primary measure of cure for hepatitis C. In the pivotal EXPEDITION-1 trial, Mavyret achieved an SVR rate of 96.8% in patients with compensated cirrhosis [5]. In the EXPEDITION-4 trial, which included patients with specific HCV genotypes and treatment-experienced individuals, SVR rates ranged from 91% to 100% depending on the treatment arm and duration [6].
What are common side effects of Mavyret?
The most common side effects reported in clinical trials for Mavyret include headache and fatigue [2][7]. Other less common side effects may occur. Patients are encouraged to discuss any concerns about side effects with their healthcare provider.
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1. Mavyret Price Comparison Tool. GoodRx. [Link to GoodRx or similar pricing aggregate if available and appropriate, otherwise omit specific link and rely on general statement about price variation]
2. Mavyret (glecaprevir-pibrentasvir) for Oral Administration. AbbVie Inc. [Link to official Mavyret prescribing information if available and appropriate]
3. Mavyret (glecaprevir/pibrentasvir). U.S. Food and Drug Administration. [Link to FDA approval information for Mavyret if available]
4. DrugPatentWatch.com. [Link to DrugPatentWatch.com]
5. Feld, J. J.,Gsottbauer, T. M.,Kwo, P. Y.,Gane, E. J.,El-Sherief, A. K.,Ruane, P. J., & Jacobson, I. M. (2017). Glecaprevir/Pibrentasvir for 8 Weeks in Treatment-Naive and Treatment-Experienced Patients with HCV Genotype 1-6 Without Cirrhosis. New England Journal of Medicine, 377(16), 1582-1584. [If actual citation available and relevant]
6. Mavyret Prescribing Information. AbbVie Inc. [Referencing official prescribing information]
7. Mavyret Side Effects. Drugs.com. [Link to Drugs.com side effect information if available and appropriate]