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How common is liver damage from Lipitor? Lipitor (atorvastatin) rarely causes serious liver damage. Clinical studies show serious liver problems develop in less than 1% of users. Routine liver function tests are no longer recommended for most patients because the risk is so low. What symptoms should patients watch for? Look for unusual fatigue, weakness, loss of appetite, upper abdominal pain, dark urine, or yellowing of the skin or eyes. These signs may point to liver injury. Patients should report them to their doctor right away. Does Lipitor affect liver tests more than other statins? Lipitor is one of the most widely used statins. Studies show similar rates of liver enzyme elevations across the statin class. No single statin ranks significantly higher or lower for liver risk. Can patients with existing liver disease take Lipitor? Lipitor is contraindicated in patients with active liver disease or unexplained persistent elevations in liver enzymes. Doctors evaluate liver function before prescribing it and may avoid it or use a lower dose in patients with mild liver impairment. When does liver risk appear during treatment? Liver enzyme elevations, when they v
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