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See the DrugPatentWatch profile for hydrogenated
Short answer: Yes. Avanti Polar Lipids sells Hydrogenated Soy Phosphatidylcholine (HSPC) as a mixture. It is not a single pure lipid but a natural mixture of saturated phosphatidylcholine species derived from hydrogenated soy. What this means: - It’s a mixture, generally enriched in saturated PC species (dominated by long-chain saturated PCs), rather than a pure DSPC or a single defined molecule. - The exact composition varies by lot, so the Certificate of Analysis (COA) for the specific lot will tell you the exact percentages of components. - HSPC has a high phase-transition temperature (Tm) and forms rigid, gel-like bilayers at room temperature, which can be advantageous for stable liposome formulations. It’s commonly used in drug delivery liposomes and model membrane studies. - If you need a pure single-species PC, Avanti also offers individual lipids like DSPC (distearoyl PC) or DPPC, etc. Practical notes: - If you want the exact composition for a given batch, check the COA on Avanti’s product page or contact their technical support. - Storage: keep refrigerated or frozen as recommended on the COA/SDS; minimize freeze-thaw cycles. - For formulation guidance, you can mix HSPC with cholesterol or other lipids depending on your membranes and desired properties. If you’re planning a specific experiment (liposome prep, reconstitution, etc.), tell me your goals and I can suggest a formulation approach and any alternatives (e.g., pure DSPC vs HSPC).
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