Diclofenac sodium topical solution is a nonsteroidal anti-inflammatory drug (NSAID) applied to the skin to help relieve pain from osteoarthritis of the knee. A common brand/formulation is diclofenac sodium topical solution (often called Pennsaid in the U.S.), which contains diclofenac sodium in a topical vehicle.
Key points:
- How it’s used: For adults with osteoarthritis of the knee. Apply to the knee(s) as directed on the label.
- Dose (typical): 2 mL applied to the affected knee twice daily. If treating both knees, apply 2 mL to each knee twice daily.
- How to apply: Use clean, dry skin over the knee. Apply the solution to the knee and rub in as directed until dry. Wash your hands after applying (unless you’re treating the hand or wrist). Do not apply to broken or irritated skin, and avoid getting the medicine in your eyes, mouth, or nose. Let it dry before covering the area or applying other products to the same area.
- What to avoid: Do not use with other diclofenac products or other NSAIDs unless advised by your clinician. Avoid heat, sun exposure, or tight bandaging on the treated area unless instructed.
- Side effects: Common are application-site reactions such as redness, itching, burning, or rash. Some people may have dermatitis. If you notice severe skin reactions, swelling, dizziness, or any signs of an allergic reaction, stop using it and seek medical help.
- Safety notes:
- May cause systemic NSAID effects (less common with topical use, but still possible): stomach upset, increased blood pressure, kidney effects, or bleeding in some people.
- Contraindications: allergy to diclofenac or other NSAIDs; active GI ulcers/bleeding; certain serious heart, kidney, or liver problems; pregnancy in later stages (risk to the fetus); and in some other conditions—follow the product label and your clinician’s guidance.
- Pregnancy and breastfeeding: Consult a healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding.
- When to see a clinician: If you experience severe stomach pain, black stools, vomiting blood, chest pain, shortness of breath, swelling of the legs, unusual weight gain, severe skin reactions, or if your OA symptoms persist or worsen.
If you’re asking about a specific product, country, or you’d like dosing for a different joint (e.g., knee vs. hand) or want alternatives (like diclofenac gel or other NSAIDs), tell me which product you have and your location, and I can tailor the details.