See the DrugPatentWatch profile for Triesence
What is Triesence injection used for?
Triesence is an intravitreal injection (it’s put directly into the eye). It contains the corticosteroid triamcinolone acetonide and is used to treat certain inflammatory eye conditions and macular swelling when a steroid can help reduce fluid and inflammation in the retina/macula. [1]
How does Triesence work?
Triamcinolone is a steroid that reduces inflammation inside the eye. In conditions that cause swelling of the macula, lowering inflammation can reduce leakage and fluid buildup, which helps improve or stabilize vision for some patients. [1]
How is Triesence given?
Triesence is administered as an injection into the vitreous cavity of the eye by an eye care professional. This is done in a clinical setting using sterile technique. [1]
What side effects do people ask about?
Common steroid-injection concerns for the eye include increased eye pressure (intraocular pressure) and cataract risk. Other potential risks with any intravitreal injection include infection and bleeding, though these are less common. Patients should discuss side effects and warning signs with their clinician. [1]
How quickly does it start working, and how long does it last?
The effect depends on the underlying eye condition and the individual. Steroid treatment in the eye is typically aimed at improving macular swelling after injection, but duration can vary and repeat treatments may be needed for some patients. [1]
Who should not use Triesence (or who needs extra caution)?
Steroid use in the eye requires caution in people with certain eye conditions (for example, uncontrolled glaucoma/raised eye pressure) or active infections in/around the eye. Your ophthalmologist will screen for contraindications and monitor response. [1]
Alternatives: what other treatments might be used instead?
Depending on the diagnosis, clinicians may use other intravitreal therapies such as anti-VEGF injections for macular edema from retinal vascular disease, or other steroid options, depending on the cause of swelling and patient factors. [1]
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Sources
[1] https://www.ema.europa.eu/en/medicines/human/EPAR/triesence