What is the half life of cosentyx?

What is Cosentyx’s (secukinumab) half-life?

Cosentyx (secukinumab) has an elimination half-life of about 27 days in adults. [1]

Half-life vs. dosing schedule: how does this affect treatment timing?

Because secukinumab remains in the body for weeks, dosing can be spaced out after the initial loading period. Cosentyx’s standard regimen includes an initial phase followed by maintenance dosing, consistent with its long half-life. [1]

Does the half-life change by patient factors?

Half-life can vary somewhat between individuals, but the commonly cited adult elimination half-life remains around 27 days. [1]

Sources

1. FDA Prescribing Information for Cosentyx (secukinumab) (section on pharmacokinetics/half-life): https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=125163