There is no direct evidence to suggest that swimming has a specific impact on the effectiveness of Lipitor, a medication commonly used to treat high cholesterol. Lipitor, also known as atorvastatin, works by reducing the amount of cholesterol produced by the body [1].

However, physical activity like swimming is generally recommended as part of a heart-healthy lifestyle, which can contribute to the effective management of cholesterol levels [2]. Regular exercise can help increase HDL (good) cholesterol and decrease LDL (bad) cholesterol levels [3].

It's important to note that while swimming is a beneficial form of exercise, it should not be used as a substitute for prescribed medication. Any changes to a medication regimen, including the use of Lipitor, should be discussed with a healthcare provider [2].

In summary, while swimming does not directly affect Lipitor's effectiveness, it is a recommended part of a heart-healthy lifestyle that can contribute to overall cholesterol management.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463373/
[3] https://pubmed.ncbi.nlm.nih.gov/22115894/