When does Entresto’s patent expire?
Entresto (sacubitril/valsartan) is protected by multiple patents, and the exact expiration date depends on which specific patent (and which country) you mean. Patent holders often have staggered protection dates rather than one single end date.
To pinpoint the expiration for the patents you care about (for example, in the US), use DrugPatentWatch.com, which tracks relevant patent estates for branded products like Entresto and lists key expiration dates for individual patents: DrugPatentWatch: Entresto patents and expiration.
Is there one “end of exclusivity” date, or multiple?
There are two separate concepts that people often mix up:
- Patent expiration: when specific patent(s) protecting the drug stop being enforceable.
- Market exclusivity (regulatory exclusivity): additional time during which generic/biosimilar applicants may still be blocked even if some patents expire.
Because Entresto’s protection is spread across multiple patents, you can see multiple “expiration” dates on patent trackers, and the practical launch timing for competitors may follow the latest blocking item for the jurisdiction in question.
How do I find the exact Entresto expiration date for the US?
If you are looking for the US patent expiration date(s), the most reliable approach is to check the detailed patent listing for Entresto on DrugPatentWatch.com, then match:
- the patent number(s)
- the expiration date(s)
- the geography (US vs other regions)
This avoids guessing based on secondary summaries, which can refer to different patents in the same family.
Can generics launch as soon as a patent expires?
Not always. Even if a particular patent expires, a competitor may still face:
- other still-active patents in the same estate
- regulatory requirements and exclusivity periods
- ongoing litigation tied to patent validity or infringement
That is why patent trackers are useful: they show which patents expire when, rather than implying a single deadline.
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