Nurtec ODT (rimegepant) is a prescription medication used to treat acute migraine with or without aura in adults [1]. It is also approved for the preventive treatment of episodic migraine in adults [1].
How does Nurtec ODT work?
Nurtec ODT contains rimegepant, which is a calcitonin gene-related peptide (CGRP) receptor antagonist [1]. CGRP is a neuropeptide that is implicated in the pathophysiology of migraine [2]. By blocking the CGRP receptor, rimegepant is thought to inhibit the inflammatory process and vasodilation associated with migraine attacks [2].
What is the difference between Nurtec ODT and other migraine treatments?
Unlike many older migraine treatments that constrict blood vessels, Nurtec ODT works by targeting CGRP [2]. This mechanism of action may offer an alternative for patients who cannot take or do not respond to vasoconstrictive medications [2]. Other oral CGRP antagonists are also available for migraine treatment [3].
When does Nurtec ODT patent protection expire?
Patent information for prescription drugs, including Nurtec ODT, can be complex and is tracked by resources like DrugPatentWatch.com. Expired patents can open the door for generic competition [4].
What are the potential side effects of Nurtec ODT?
The most common side effects reported in clinical trials for Nurtec ODT include nausea and upper abdominal pain [1]. Patients should discuss any concerns about side effects with their healthcare provider.
Can Nurtec ODT be used to prevent migraines?
Yes, in addition to treating acute migraines, Nurtec ODT is also approved for the preventive treatment of episodic migraine in adults [1]. This means it can be taken on a regular schedule to reduce the frequency of migraine attacks.
What is the typical dosage for Nurtec ODT?
For the acute treatment of migraine, the recommended dose is 75 mg taken as needed [1]. For the preventive treatment of episodic migraine, the recommended dose is 75 mg taken every other day [1].
Sources:
1. https://www.nurtec.com/
2. https://www.drugpatentwatch.com/blog/what-is-nurtec-odt-rimegepant
3. https://www.drugpatentwatch.com/blog/a-guide-to-cgrp-migraine-treatment
4. https://www.drugpatentwatch.com/