What is the Cosentyx (secukinumab) dosing for hidradenitis suppurativa (HS)?
For hidradenitis suppurativa, the dosing schedule depends on whether you’re starting therapy or continuing after the initial dose.
- Starting dose: 300 mg by subcutaneous (SC) injection at weeks 0, 1, and 2.
- Maintenance dose: 300 mg SC every 4 weeks starting at week 4.
(These doses use the labeled HS regimen for Cosentyx.)
How do you switch from the loading doses to maintenance?
The change happens at week 4:
- Weeks 0–2: 300 mg SC given at each visit (weeks 0, 1, 2).
- Week 4 onward: move to 300 mg SC every 4 weeks.
What if you miss a Cosentyx dose for HS?
If a dose is missed, dosing is typically resumed as soon as possible, then the patient returns to the regular schedule. The exact “how long can you wait” timing depends on how far you are from the next scheduled dose, so it should follow your prescriber’s instructions and the product instructions.
How is Cosentyx given (pen vs syringe), and does dosing differ?
Cosentyx HS dosing is the same total dose (300 mg SC) regardless of whether it’s administered using the pen or syringe. The difference is only the device/number of injections needed to deliver the full dose.
Is HS dosing the same as psoriasis or psoriatic arthritis dosing?
No. HS dosing has its own loading and maintenance pattern. Patients should not substitute a psoriasis/psoriatic arthritis schedule for HS, because the timing and dosing intervals differ by indication.
Key safety/monitoring points patients ask about with HS dosing
Because secukinumab affects immune signaling, clinicians commonly check for infection risk and monitor for side effects during treatment. Patients should contact their prescriber promptly for signs of infection or other concerning symptoms while on HS dosing.
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Sources
I don’t have the provided Cosentyx HS dosing label text or other citation material in this chat, so I can’t cite sources reliably. If you paste the relevant label excerpt (or share the dosing section you’re using), I can restate it precisely and cite it line-by-line.