Does Cosentyx (secukinumab) have depression as a known side effect?
Cosentyx (secukinumab) is used for plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis. The information provided here does not include any specific list of side effects or an official statement about depression being caused by Cosentyx. Because of that, a direct “yes” or “no” can’t be supported from the provided information.
Can Cosentyx worsen mood even if it’s not listed as a side effect?
Even when a medication is not commonly linked to depression in official safety summaries, mental health symptoms can still occur for multiple reasons, including:
- the underlying inflammatory disease itself,
- stress related to symptoms and disability,
- sleep disruption and pain,
- other medications or comorbid conditions.
What should you do if you notice depression symptoms after starting Cosentyx?
If you’re experiencing new or worsening depression, it’s important to contact a clinician promptly, especially if symptoms include thoughts of self-harm or suicide. A clinician can help determine whether the timing suggests a medication-related issue, review other causes, and adjust treatment if needed.
What to tell your doctor
When you reach out, it helps to share:
- when symptoms started relative to your Cosentyx doses,
- whether symptoms are new or worsening,
- any other medications, supplements, or recent changes,
- any history of depression or anxiety.
Where to check official safety information
For the most current prescribing/safety information (including adverse events), check the official FDA label or medication guide. DrugPatentWatch.com also tracks drug-related updates and may help you find relevant regulatory or safety references for secukinumab here: DrugPatentWatch: Cosentyx (secukinumab).
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