Advil is a nonsteroidal anti-inflammatory drug (NSAID) that contains ibuprofen as its active ingredient. It is used to relieve pain, fever, and inflammation. While Advil is generally safe when taken as directed, there are some potential side effects associated with frequent use.

According to GoodRx [2], the most common side effects of Advil are stomach pain, nausea, and heartburn. These symptoms can be exacerbated by taking the medication on an empty stomach. In rare cases, Advil can cause more serious side effects, such as stomach ulcers, bleeding, or perforation. These complications are more likely to occur in people who take high doses of Advil for extended periods of time.

Drug Patent Watch [1] notes that Advil can also cause kidney damage, especially in people who already have kidney problems or who take other medications that can affect kidney function. In addition, Advil can interact with other medications, such as blood thinners, and increase the risk of bleeding.

The Australian Drug Foundation [3] also warns that Advil can cause allergic reactions in some people, including hives, rash, and swelling of the face, lips, tongue, or throat. People who have asthma may be at increased risk of having an allergic reaction to Advil.

It is important to note that these side effects are not unique to Advil and can occur with other NSAIDs as well. To minimize the risk of side effects, it is recommended to take Advil only as directed and to avoid taking it for extended periods of time. If you experience any unusual symptoms while taking Advil, such as severe stomach pain or difficulty breathing, you should seek medical attention immediately.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/ADVIL
[2] https://www.goodrx.com/advil/advil-side-effects
[3] https://adf.org.au/drug-facts/ibuprofen/