Cosentyx (secukinumab) and Humira (adalimumab) are both medications used to treat various inflammatory conditions, such as psoriasis, psoriatic arthritis, and ankylosing spondylitis. According to available information, Cosentyx and Humira have shown similar efficacy in treating these conditions, but there are some differences in their success rates and administration methods.

Cosentyx has demonstrated high efficacy in treating psoriasis, with approximately 80-90% of patients achieving clear or almost clear skin after nearly a year of treatment [1]. In comparison, Humira has shown similar efficacy, with around 60-80% of patients achieving a 75% improvement in psoriasis symptoms after 16 weeks of treatment [2]. However, Humira's efficacy may vary depending on the specific inflammatory condition it is used to treat.

It is important to note that both Cosentyx and Humira have their own advantages and disadvantages. Cosentyx is administered through injections every 4 weeks, while Humira requires more frequent injections (every 1-2 weeks) [3][4]. Additionally, Humira has been associated with a higher risk of serious infections and certain types of cancer compared to Cosentyx [5].

In terms of cost, Cosentyx and Humira are both expensive medications, with annual costs ranging from $30,000 to $50,000 [6]. However, the patents for both drugs have expired or are set to expire soon, which may lead to the introduction of generic versions and a potential reduction in costs [7][8].

In summary, Cosentyx and Humira have demonstrated similar efficacy in treating inflammatory conditions, but Cosentyx may have a slightly higher success rate in treating psoriasis. Differences in administration frequency, side effects, and cost are also factors to consider when comparing the two medications.

Sources:

1. Novartis. (2021). COSENTYX® (secukinumab) [Prescribing Information]. Available at: <https://www.pharma.us.novartis.com/sites/www.pharma.us.novartis.com/files/cosentyx.pdf>
2. AbbVie. (2021). HUMIRA® (adalimumab) [Prescribing Information]. Available at: <https://www.rxabbvie.com/pdf/humira.pdf>
3. Mayo Clinic. (2021). Psoriasis: Treatments and drugs. Available at: <https://www.mayoclinic.org/diseases-conditions/psoriasis/diagnosis-treatment/drc-20355842>
4. American College of Rheumatology. (2021). Medications for Psoriatic Arthritis. Available at: <https://www.rheumatology.org/I-Am-A/Patient-Caregiver/Treatments/Medications/Drug-Types/Biologics/Secukinumab-Cosentyx>
5. National Psoriasis Foundation. (2021). Comparing Biologics. Available at: <https://www.psoriasis.org/treatments/biologics/comparing-biologics>
6. GoodRx. (2021). Cosentyx vs. Humira: Which is Cheaper? Available at: <https://www.goodrx.com/blog/cosentyx-vs-humira/>
7. DrugPatentWatch. (2021). Secukinumab (Cosentyx) Patent Expiration & Generics. Available at: <https://www.drugpatentwatch.com/patent/secukinumab/>
8. DrugPatentWatch. (2021). Adalimumab (Humira) Patent Expiration & Generics. Available at: <https://www.drugpatentwatch.com/patent/adalimumab/>