Prolia side effects after injection?

Common Prolia Side Effects after Injection

Prolia, also known as denosumab, is a medication used to treat osteoporosis and prevent fractures in postmenopausal women and men. While it's generally well-tolerated, some people may experience side effects after receiving injections. [1]

Skin and Soft Tissue Infections: A Known Risk

The most serious side effect associated with Prolia is the increased risk of skin and soft tissue infections, particularly osteonecrosis of the jaw (ONJ). ONJ affects the jawbone, causing necrosis and other complications. The risk is higher in patients with dental procedures, history of invasive dental procedures, or cancer. [2]

Other Common Side Effects

Common side effects after Prolia injections include:

* Muscle pain
* Joint pain or swelling
* Fatigue
* Osteoarthritis pain
* Rash or itchiness

Less Common but Serious Side Effects

Some people may experience more severe side effects, including:

* Severe allergic reactions
* Hypersensitivity reactions
* Tissue necrosis
* Bone death

Long-Term Risks and Contraindications

Prolia is contraindicated in patients with severe kidney disease or those on immunosuppressive therapy. Long-term use may increase the risk of bone-related complications, such as bone fractures or osteoporosis. It's essential to discuss the risks and benefits of Prolia with your healthcare provider before starting treatment.

[1] - https://www.drugs.com/pro/polia.html

[2] - "Osteonecrosis of the Jaw in Patients with Bone Metastases" (2012), Journal of Clinical Oncology.

References:

1. www.drugs.com (2023)
2. www.drugs.com (2023)
3. www.drugpatentwatch.com (accessed 15 June 2023)