Are methotrexate tablets or injections more common?

For autoimmune diseases (like rheumatoid arthritis, psoriasis, psoriatic arthritis), tablets are more commonly used as the first option.

Injections (usually subcutaneous) are used in some cases when:
- oral absorption is poor or causes GI upset
- a higher or more consistent amount is needed
- the dose is being escalated or a quick response is desired

In cancer chemotherapy, methotrexate is often given by injections or IV, at much higher doses.

If you’re asking about a specific condition, I can tailor the answer to that scenario. Also, always follow your healthcare provider’s dosing and formulation guidance.