Standard Storage for Lurbinectedin
Lurbinectedin (Zepzelca), an injection for small cell lung cancer, requires refrigeration at 2°C to 8°C (36°F to 46°F). Keep it in its original carton to protect from light until use.[1]
What If Refrigeration Isn't Available?
Unopened vials remain stable for up to 14 days at 20°C to 25°C (68°F to 77°F) if needed for transport or short-term issues. Discard if exposed longer or to freezing.[1]
Handling After Reconstitution
Once mixed with saline, use immediately. If not, refrigerate the solution at 2°C to 8°C and infuse within 24 hours. Do not freeze the reconstituted product.[1]
Why These Temperatures Matter
Heat or light degrades the drug's potency, risking reduced efficacy. Freezing can cause vial breakage or precipitation. Pharmacies and patients follow these to maintain stability per FDA labeling.[1]
[1]: Zepzelca Prescribing Information