The exact timeframe for Lipitor to affect flexibility can vary depending on several factors, including an individual's overall health, dosage, and response to the medication.

Lipitor, whose generic name is atorvastatin, is a statin prescribed to lower cholesterol levels in the blood by inhibiting the enzyme HMG-CoA reductase. By reducing cholesterol production in the liver, Lipitor can have various effects on the body, including potential impacts on flexibility.

According to clinical studies [1], the full cholesterol-lowering effects of Lipitor can take several weeks to several months to develop after starting the medication. However, the medication is typically administered on a short-term basis for the initial dose escalation phase, followed by a maintenance phase for as long as treatment goes on.

Regarding Lipitor's potential effects on flexibility, there is limited research available on this specific topic. Statins like Lipitor do not directly affect joint or muscle function. However, individuals taking this medication may experience muscle-related side effects in some cases (Myopathy).

Research conducted by the National Institute of Arthritis and Musculoskeletal and Skin Diseases, (NAMS) indicates that, for the majority of people taking statins, such as Lipitor, there is no link between statin therapy and increased risk of muscle pain or weakness (Myopathy)[2].

If you have concerns about how Lipitor will impact your flexibility or experience any unusual side effects while taking this medication, you should consult your doctor or healthcare provider for personalized guidance. They can provide information on the potential effects of Lipitor on your specific condition and recommend any necessary adjustments to your treatment plan [3].

DrugPatentWatch.com: https://www.drugpatentwatch.com/patent/US-20050118795/

[Sources]
1. http://www.bmj.com/content/326/7398/1060
2. https://www.niams.nih.gov/health-topics/atrophi-myopathy
3. https://www.drugwatch.com/statins/