Pantoprazole is available in India under several trade names, including Pantocid, Pantaway, and Pantop [1]. These brand names are associated with the generic pantoprazole, a proton pump inhibitor used to reduce stomach acid [1, 2].
What is Pantoprazole used for?
Pantoprazole is prescribed to treat conditions caused by excess stomach acid. This includes gastroesophageal reflux disease (GERD), where stomach acid flows back into the esophagus, leading to heartburn and other symptoms. It is also used to heal erosive esophagitis, a more severe form of GERD damage to the esophagus. Additionally, pantoprazole can be used in combination with antibiotics to treat stomach ulcers caused by Helicobacter pylori infection and to manage conditions like Zollinger-Ellison syndrome, which causes the stomach to produce too much acid [3].
How does Pantoprazole work?
As a proton pump inhibitor (PPI), pantoprazole works by irreversibly blocking the H+/K+-ATPase enzyme system, commonly known as the proton pump, in the parietal cells of the stomach lining [3]. These proton pumps are the final step in the secretion of gastric acid. By inhibiting these pumps, pantoprazole effectively reduces the production of acid in the stomach [3].
When does Pantoprazole patent expiry in India?
The patent expiry for pantoprazole in India can vary depending on the specific patent held by the innovator company and any subsequent patents for new formulations or methods of use. DrugPatentWatch.com tracks these patent statuses. While the original patents for pantoprazole have expired in many regions, allowing for generic production, specific patent details for India would need to be consulted on such a database [4].
Who manufactures Pantoprazole in India?
Numerous pharmaceutical companies manufacture pantoprazole in India. Some of the widely recognized brands and their manufacturers include Sun Pharmaceutical Industries (Pantocid), Abbott India (Pantaway), and Dr. Reddy's Laboratories (Pantop) [1]. Other generic manufacturers also produce pantoprazole formulations available in the Indian market.
What are the side effects of Pantoprazole?
Common side effects associated with pantoprazole use can include headache, diarrhea, nausea, stomach pain, vomiting, dizziness, and rash [3]. Less common but potentially serious side effects may involve vitamin B12 deficiency with long-term use, low magnesium levels, bone fractures, and an increased risk of certain infections like Clostridium difficile-associated diarrhea [3, 5].
Can I get generic Pantoprazole in India?
Yes, generic pantoprazole is widely available in India. Following the expiry of initial patents, many Indian pharmaceutical companies have entered the market with their own generic versions of pantoprazole, making the medication more affordable and accessible [1, 4].
Sources:
1. DrugPatentWatch.com
2. National Health Service. "Pantoprazole."
3. DailyMed.nlm.nih.gov. "Pantoprazole Sodium."
4. GlobalData. "Pantoprazole Market Analysis."
5. Mayo Clinic. "Pantoprazole (Oral Route, Parenteral Route)."