Lipitor (atorvastatin) is a medication used to lower cholesterol levels in the blood. According to the information provided by Drug Patent Watch [1], there is no specific recommendation against taking Lipitor with high-fat foods. However, it is important to note that high-fat foods can interfere with the absorption of the medication and reduce its effectiveness. Therefore, it is recommended to take Lipitor with a low-fat meal or on an empty stomach to ensure optimal absorption [2].
A study published in the Journal of Pharmacy and Pharmacology [3] evaluated the effect of food on the pharmacokinetics of atorvastatin. The results showed that the absorption of atorvastatin was reduced by approximately 32% when taken with a high-fat meal compared to a low-fat meal. Therefore, it is recommended to take Lipitor with a low-fat meal or on an empty stomach to ensure optimal absorption and effectiveness.
In conclusion, while there is no specific recommendation against taking Lipitor with high-fat foods, it is recommended to take it with a low-fat meal or on an empty stomach to ensure optimal absorption and effectiveness. Patients should consult with their healthcare provider for specific recommendations on how to take Lipitor and manage their cholesterol levels.
Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766553/
[3] https://pubmed.ncbi.nlm.nih.gov/21269482/