Biohaven Pharmaceuticals is the current marketer of Nurtec ODT in the U.S. [1] In 2023, Pfizer acquired Biohaven Pharmaceuticals, and thus Pfizer is now the marketer of Nurtec ODT. [1]
What is Nurtec ODT?
Nurtec ODT (rimegepant) is an orally disintegrating tablet used for the acute treatment of migraine with or without aura in adults. [1] It is also indicated for the preventive treatment of episodic migraine in adults. [1]
When will Nurtec ODT lose patent protection?
The patent protection for Nurtec ODT is a complex issue with multiple patents and ongoing litigation. As of early 2024, DrugPatentWatch.com tracks several patents related to Nurtec ODT. [2] For example, U.S. Patent No. 10,828,151, which covers certain formulations of rimegepant, is set to expire in 2026. [2] However, other patents cover different aspects of the drug, and their expiry dates vary. [2] Litigation surrounding these patents can also impact market exclusivity. [3]
Can generic versions of Nurtec ODT be sold before patent expiry?
The ability for generic versions of Nurtec ODT to enter the market before patent expiry typically depends on the outcome of patent litigation and any specific exclusivities granted by regulatory bodies. Companies often challenge patents to clear the way for generic competition. [3]
Who are Nurtec ODT's competitors?
Nurtec ODT competes with other acute and preventive migraine treatments. In the acute treatment space, competitors include triptans, ditans, and other CGRP antagonists. For preventive treatment, it competes with other CGRP monoclonal antibodies and older classes of preventive medications. [4]
What is the mechanism of action for Nurtec ODT?
Nurtec ODT works by blocking the activity of calcitonin gene-related peptide (CGRP). CGRP is a molecule involved in migraine pathways. By blocking CGRP, Nurtec ODT helps to reduce inflammation and dilate blood vessels in the brain, which are associated with migraine pain. [1]
What clinical data supports Nurtec ODT's effectiveness?
Clinical trials have demonstrated Nurtec ODT's efficacy in treating both the acute and preventive aspects of migraine. Studies showed that a significant percentage of patients experienced pain freedom and the absence of their most bothersome migraine symptom two hours after taking Nurtec ODT for acute treatment. For preventive treatment, trials indicated a reduction in monthly migraine days. [1]
What are the potential side effects of Nurtec ODT?
Common side effects reported in clinical trials include nausea and abdominal pain. [1] Patients should discuss any concerns about side effects with their healthcare provider. [1]
How is Nurtec ODT administered?
Nurtec ODT is an orally disintegrating tablet that dissolves on the tongue, allowing for administration without water. [1]
What is the current pricing or insurance coverage for Nurtec ODT?
Information regarding the current pricing and insurance coverage for Nurtec ODT can vary. Patients are often advised to check with their insurance provider or visit the manufacturer's website for the most up-to-date details on patient assistance programs and co-pay information. [5]
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**Sources:
1. Pfizer
2. DrugPatentWatch.com
3. Biohaven Pharmaceuticals
4. Various pharmaceutical industry reports
5. Manufacturer's patient support information