The price of isavuconazonium sulfate, marketed as Cresemba, can vary significantly depending on factors such as dosage, quantity, insurance coverage, and pharmacy. There is no single fixed price for the medication.
How much does Cresemba typically cost without insurance?
Without insurance, the retail price for a 30-day supply of isavuconazonium sulfate capsules (e.g., 200 mg) can range from approximately $6,000 to over $8,000 [1]. For intravenous (IV) formulations, the cost can also be substantial, with a 14-day supply potentially costing several thousand dollars [1]. These figures are estimates and can fluctuate based on the pharmacy and location.
Are there patient assistance programs for Cresemba?
Yes, Astellas Pharma, the manufacturer of Cresemba, offers a co-pay assistance program for eligible commercially insured patients [2]. This program, known as the Cresemba Co-pay Savings Program, can help reduce out-of-pocket costs for patients who meet specific criteria. Details on eligibility and how to apply are typically available through the manufacturer's website or by speaking with a healthcare provider [2].
What is the typical insurance coverage for isavuconazonium sulfate?
Insurance coverage for isavuconazonium sulfate can vary widely. Many insurance plans may cover the medication, but typically require prior authorization. Patients may also have a co-pay or co-insurance, which represents their out-of-pocket expense after the insurance company has paid its portion. The formulary status of Cresemba on different insurance plans will determine the level of coverage and the patient's financial responsibility.
How does the cost of Cresemba compare to other antifungal medications?
Cresemba is considered a newer generation azole antifungal, and its pricing often reflects the cost associated with novel drug development and clinical trials. Compared to older antifungal agents, newer medications may have a higher initial price point. However, factors such as efficacy, safety profile, and treatment duration can influence the overall cost-effectiveness of a particular antifungal therapy. A direct cost comparison would need to account for these clinical variables in addition to the drug's price.
What are the different forms and strengths of isavuconazonium sulfate available?
Isavuconazonium sulfate is available in two formulations: an oral capsule and an intravenous (IV) solution [3]. The oral capsules are typically available in strengths of 100 mg and 200 mg [3]. The IV solution is prepared for administration by a healthcare professional. The prescribed dosage and formulation will impact the overall cost of treatment.
When was isavuconazonium sulfate approved?
Isavuconazonium sulfate was approved by the U.S. Food and Drug Administration (FDA) for the treatment of invasive aspergillosis and invasive mucormycosis in adults in February 2015 [4]. This approval timeline is relevant for understanding its market presence and pricing history relative to other treatments.
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Sources:
1. https://www.goodrx.com/cresemba
2. https://www.cresemba.com/savings-support
3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/206308lbl.pdf
4. https://www.fda.gov/drugs/drug-approvals-and-databases/fda-drug-safety-communication-approved-new-drug-treatment-invasive-aspergillosis-and-invasive-mucormycosis