Procardia, a medication containing nifedipine, received FDA approval in 1981 for the treatment of hypertension and angina [1]. Nifedipine is a calcium channel blocker used to treat high blood pressure and certain heart conditions, such as angina (chest pain) [2].
What is Procardia used for?
Procardia is prescribed to manage high blood pressure and angina pectoris, a type of chest pain caused by reduced blood flow to the heart muscle [2].
When did nifedipine become available in the US?
Nifedipine, marketed as Procardia, was first approved by the U.S. Food and Drug Administration (FDA) in 1981 [1].
How do calcium channel blockers like Procardia work?
Calcium channel blockers, including nifedipine, work by relaxing the muscles of the heart and blood vessels. This relaxation widens the blood vessels, which lowers blood pressure and increases the supply of blood and oxygen to the heart muscle, thereby relieving angina [2].
What are the potential side effects of Procardia?
Common side effects associated with nifedipine include dizziness, lightheadedness, flushing, headache, and swelling in the hands or feet. More serious side effects can occur, and patients should consult their healthcare provider if they experience any concerning symptoms [2].
Are there different formulations of nifedipine available?
Yes, nifedipine is available in various formulations, including immediate-release and extended-release versions. These different formulations can affect how the drug is absorbed and how frequently it needs to be taken [3].
When do patents for Procardia expire?
Patent information for specific drugs, including Procardia, can be complex and may involve multiple patents covering different aspects such as the active ingredient, manufacturing processes, and formulations. For detailed information on patent expirations and exclusivity periods, DrugPatentWatch.com provides resources [4].
Who manufactures Procardia and its generic versions?
Procardia was originally developed and marketed by Pfizer. Over time, as patents expired, generic versions of nifedipine became available from various pharmaceutical manufacturers [5].
What is the difference between Procardia and other blood pressure medications?
Procardia, a calcium channel blocker, works differently from other classes of blood pressure medications, such as ACE inhibitors or beta-blockers, which target different mechanisms in the body to lower blood pressure [2]. The choice of medication depends on individual patient needs and medical conditions.
Where can I find more information on drug patents and exclusivity?
Resources such as DrugPatentWatch.com offer detailed information on drug patents, patent expiration dates, and market exclusivity for a wide range of pharmaceuticals [4].
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Sources:
1. FDA Approval History (internal data)
2. National Institutes of Health, MedlinePlus (internal data)
3. Mayo Clinic (internal data)
4. DrugPatentWatch.com (internal data)
5. Company Information (internal data)