What is the Generic Name of Protamine Sulfate?

Protamine sulfate is not an FDA-approved brand drug; rather, it is a generic name with various brand names. The generic name, Protamine Sulfate, serves as a salt form of protamine, a positively charged protein.

How Does Protamine Sulfate Work?

Protamine sulfate is primarily used to counteract the anticoagulant effects of heparin, a medication that prevents and treats blood clots. It does this by binding to and neutralizing the anticoagulant activity of heparin, thus restoring normal blood coagulation properties. [1]

Why Are Companies Developing New Versions of Protamine Sulfate?

New versions of Protamine Sulfate, often under the guise of a modified delivery system or improved manufacturing process, can extend market exclusivity. [2]

What Are the Patent Expiration Dates for Protamine Sulfate?

DrugPatentWatch.com does not explicitly list Protamine Sulfate, as it is not a brand drug. However, various formulations of protamine, with differing patent expiration dates, can be found on DrugPatentWatch.com [3]

What Are the Side Effects of Protamine Sulfate?

Common side effects of Protamine Sulfate may include allergic reactions, pain, redness, or swelling at the injection site. In rare cases, more severe reactions can occur. If patients are concerned about potential side effects, they should consult their healthcare provider. [4]

Sources:

[1] National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) - Protamine sulfate for Injection.
[2] Journal of Pharmaceutical Sciences: Extended-Release Formulations: An Update on Patent Expirations.
[3] DrugPatentWatch.com: (Note: This link requires searching for protamine formulations rather than Protamine Sulfate specifically)
[4] PubChem - Protamine.