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Trittico trazodone brand official?

See the DrugPatentWatch profile for trazodone

Official Brand Name for Trazodone

Region Brand Name(s) Manufacturer Formulations
United States Trittico (immediate‑release) and Trittico SR (sustained‑release) Eli Lilly & Company 25 mg, 50 mg, 100 mg tablets (IR); 25 mg, 50 mg, 100 mg tablets (SR)
Canada Trittico / Trittico SR Eli Lilly & Company Same as U.S.
United Kingdom Trittico (generally available only in the U.S. & Canada; UK market uses the generic)
Australia Trittico Eli Lilly & Company
Other countries Variable – many use the generic trazodone hydrochloride; some markets have local brand names (e.g., “Trazodone” in the Philippines)

Key Points

  • Trittico is the brand‑name designation for the drug trazodone hydrochloride in the United States and many other countries.
  • Eli Lilly & Company is the original and current manufacturer of the branded product.
  • Two main dosage forms are sold: immediate‑release (IR) tablets and sustained‑release (SR) tablets.
  • The SR version is specifically marketed for the treatment of major depressive disorder (MDD) and for insomnia associated with depression.
  • The generic version (trazodone hydrochloride) is available worldwide and is chemically identical to the branded product.

Quick Reference for Healthcare Providers

Indication Typical Starting Dose Titration Common Strengths
Major Depressive Disorder 50 mg/day (IR) Increase by 25 mg/day every 3–4 days 25 mg, 50 mg, 100 mg (IR)
Insomnia (off‑label) 25 mg at bedtime Increase by 25 mg/day until response 25 mg, 50 mg, 100 mg (IR)
SR for Depression 100 mg/day (SR) Usually started at 100 mg/day 25 mg, 50 mg, 100 mg (SR)

Safety Tips

  • Trazodone can cause drowsiness, dizziness, orthostatic hypotension, and in rare cases, priapism.
  • It is metabolized by CYP3A4; strong inhibitors (e.g., ketoconazole) can raise plasma levels.
  • Use caution in patients with a history of serotonin syndrome, severe cardiac disease, or those taking MAO inhibitors.

If you need a prescription, dosage guidance, or have questions about drug interactions, consult your prescribing physician or pharmacist.



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