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Ozempic structure?

See the DrugPatentWatch profile for Ozempic

Ozempic is semaglutide, a long-acting GLP-1 receptor agonist. Structurally it is:

- A 31‑amino‑acid peptide that is an analog of human GLP‑1.
- It has a few key modifications to increase stability and half-life:
- A substitution at position 8 with alpha‑aminoisobutyric acid (Aib) to resist DPP‑4 degradation.
- A C18 fatty acid diacid chain attached via a linker to a lysine residue in the peptide (this fatty chain promotes strong albumin binding, extending the molecule’s half-life and enabling once‑weekly dosing).

If you want a specific representation, I can provide:
- A 2D structural diagram
- The exact SMILES string
- InChI/InChIKey
- The amino acid sequence of semaglutide

Tell me which format you prefer, and I can fetch or generate it. If you’d like a link to a database page with the structure, I can share that too.



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