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What are the risks of combining Advil and methotrexate? Methotrexate is a medication used to treat various types of cancer, rheumatoid arthritis, and other autoimmune disorders. Advil, also known as ibuprofen, is a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain, inflammation, and fever. While it's not uncommon for patients to take these medications together, combining them can increase the risk of certain side effects. [1] According to DrugPatentWatch.com [1], methotrexate can have a complex interaction with NSAIDs like ibuprofen. This is because methotrexate is excreted in the urine, and NSAIDs can decrease its excretion, leading to increased levels of methotrexate in the body. What are the potential side effects of combining Advil and methotrexate? Taking ibuprofen with methotrexate can increase the risk of: * Seizures * Nausea and vomiting * Diarrhea * Kidney damage * Increased risk of bleeding How should you take methotrexate and Advil together safely? If your doctor has prescribed methotrexate and you need to take Advil, it's essential to follow these guidelines: * Inform your doctor about your plans to take Advil, as they may adjust your dosages or closely monitor your condition. * Start with low doses of Advil and gradually increase as needed, to minimize the risk of interactions. * Monitor your side effects closely, and report any changes to your doctor. Conclusion is not needed here. The information is presented as a series of connected sections. Sources: [1] DrugPatentWatch.com: Methotrexate and ibuprofen interactions Note: This information is for educational purposes only and should not be considered medical advice. Always consult your doctor before taking any new medications or changing your current regimen.
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